Subject: Studying SN1 and SN2 Reactions: Nucleophilic Substitutions in the saturated carbon Lab Spouse: Jeszie Geronimo
Objective and purpose: the purpose of this experiment is to convert , the burkha alcohol for an alkyl bromide using a Sn2 Reaction. Look into some factors that effect the rate of Sn1 reactions. The second component to this laboratory will concentrate more about how unlike factors influence the rate of reactions in anSN1 reactions. The factors that individuals will be examining are the leaving groups, Cl- vs . Br. The framework of the alkyl group, tertiary versus secondary and the polarity of the solvent, 40 percent 2-propanol vs . 60 percent 2-propanol. Launch: The Substitution reactions require an atom or atoms are changing one another atom. Many of these reactions require a nucleophile. Nucleophiles possess unshared pair of electrons. Weak bases are thought good living groups in Nucleophilic alternative reactions. You will find two mechanisms for these reactions are SN1 and SN2. Sn2 Mechanisms the going out of group are regularly weak bases. The carbon group the reaction goes faster if the nucleophile strategies the carbon dioxide. The nucleophiles are the better as the camp gets stronger. The solvent favors one towards a polar aprotic solvents. Sn1 Mechanisms the leaving group must be a weak foundation. The co2 group can be part of the rate determining stage. The reaction will go faster if the there are steady carbonations. The solvent party favors one to a polar protic solvents. Procedure: synthesizing 1-bromobutane
1 . Place boiling computer chip, 1-butanols, and HBr solution into test tube 2 . Slowly put concentrated H2SO4
3. Warmth at reflux for one hour
4. Allow the reactions blend to awesome, then separate the acid level 5. Rinse the organic layer with water, aqueous NaHCO3, In that case Water once again 6. Dry the organic and natural layer with anhydrous
7. Purify the product by distillation
8. Define the product by simply boiling level, refractive index, density, or IR...